Fondaparinux and Direct Oral Anticoagulants
نویسندگان
چکیده
منابع مشابه
Reversal of direct oral anticoagulants
Reversal agents for direct oral anticoagulants (DOACs), including factor X inhibitors and direct thrombin inhibitors, are a major concern in clinical practice. After DOACs were introduced and became widely used as an alternative for vitamin K antagonists in the management of venous thromboembolism and nonvalvular atrial fibrillation, the need for effective reversal agents has increased, particu...
متن کاملDirect oral anticoagulants and venous thromboembolism.
Venous thromboembolism (VTE), consisting of deep vein thrombosis and pulmonary embolism, is a major clinical concern associated with significant morbidity and mortality. The cornerstone of management of VTE is anticoagulation, and traditional anticoagulants include parenteral heparins and oral vitamin K antagonists. Recently, new oral anticoagulant drugs have been developed and licensed, includ...
متن کاملDirect oral anticoagulants and antiplatelet agents
Oral anticoagulants and platelet receptor blockers are widely used in clinical practice with the aim of reducing the risk of thrombotic complications in patients with cardiovascular diseases. Their regular intake and adequate antithrombotic action is vital and this is way numerous assays have been developed for laboratory testing and monitoring of these agents. Available assays can be stratifie...
متن کاملDirect Oral Anticoagulants and their Clinical Management
Submit Manuscript | http://medcraveonline.com Abbreviations: DOACs: Direct Oral Anticoagulants; DVT: Deep Venous Thrombosis; PE: Pulmonary Embolus; PBS: Pharmaceutical Benefits Scheme; PD: Pharmacodynamic; PK: Pharmacokinetics; TGA: Therapeutic Good Administration; PCC: Prothrombin Complex Concentrate; PT: Prothrombin Time; aPTT: Activated Atrial Thromboplastin Time; FDA: Food and Drug Administ...
متن کاملThe laboratory and the direct oral anticoagulants.
Although direct oral anticoagulants do not need laboratory testing for dose adjustment, there are instances when laboratory measurement of the drug anticoagulant effect may be useful. They include before initiation of treatment, before surgical or invasive procedures, on the occasion of hemorrhagic or thrombotic events, and whenever immediate reversal of anticoagulation is needed. Choice of tes...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2018
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2017.12.067